Immunological Aspects of Acute and Recurrent Herpes Simplex Keratitis

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Immunological Aspects of Acute and Recurrent Herpes Simplex Keratitis

Herpes simplex keratitis (HSK) belongs to the major causes of visual morbidity worldwide and available methods of treatment remain unsatisfactory. Primary infection occurs usually early in life and is often asymptomatic. Chronic visual impairment and visual loss are caused by corneal scaring, thinning, and vascularization connected with recurrent HSV infections. The pathogenesis of herpetic ker...

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Recurrent Herpes Simplex Keratitis in Penetrating Keratoplasty

Purpose and Methods: Penetrating keratoplasty (PK) in herpes simplex keratitis (HSK) is increasingly performed not only for visual purposes but also to remove viral antigen from the cornea and to reestablish the structural integrity of the eyes. With the improvement of medical management and surgical techniques which lead to a higher survival rate of the graft, PK in HSK still carries a high co...

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Treatment of Steroid-Induced Recurrent Herpes Simplex Virus Epithelial Keratitis

Steroid use is a considerable risk in recurring Herpes Simplex Virus (HSV) epithelial keratitis. This case demonstrates the efficacy of treatment with oral acyclovir followed by a maintenance dose to reduce the risk of recurrences. I. Case History a. 77yo Caucasian male b. CC: Blurry vision at distance and near OS c. Ocular Hx: (+) Corneal ulcer OS, (+) HSV epithelial keratitis OS 12/1998, 5/20...

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Epidemiology of Herpes Simplex Keratitis.

Considerable information has been accumulated concerning the herpes virus and its relationship to man, its natural host (Table VI). It is evident that to control the diseases produced, by the virus it is essential that some means be found not only to control the acute manifestations but also to eliminate the harbored virus from the readily available supply in the numerous ubiquitous carriers. A...

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Herpes Simplex Keratitis: Bilateral Effects.

Müller et al. studied corneal nerve morphology and endothelial cell density (ECD) in patients with and without unilateral herpes simplex keratitis (HSK). They demonstrated correlated reductions in corneal central ECD, subbasal nerve number and length, and sensation in both the affected and clinically unaffected contralateral eyes. They suggest a potential link between corneal innervation and en...

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ژورنال

عنوان ژورنال: Journal of Immunology Research

سال: 2014

ISSN: 2314-8861,2314-7156

DOI: 10.1155/2014/513560